Viral Hemorrhagic Fever (ebola) Essay, Research Paper
Viral Hemorrhagic Fever
How would you like it if you died. Well
that.s what.s happening to people in Africa.
Their families die around them, spreading the
deadly disease further into the ecosystem.
Killing at will, this potent filovirus sweeps
through villages with reckless abandon,
destroying anything and everything in it.s way,
and then just as mysteriously as it came, it
disappears without a trace. Even with our
modern technologies, we still don.t really know
too much about this death sentence disguised as
a virus. In the following, I will do my best to
teach you about Ebola, its cousins, where it.s
from, possible cures, effects, and so on. If we
want to, we can find a cure. We control our
destiny, and it.s up to us to find an anecdote
to this killing machine.
The Ebola virus is a highly contagious
filovirus that can be transmitted by re-use of
unsterilized syringes, needles, and directly
transferring it by contact of bodily fluids that
contain high levels, or .bricks. of virus.
Aerosol transmission cannot be counted out, but
water vapor containing secretions of Ebola are
known to spread the infection. Seeing that
Ebola can be spread in numerous ways, including
being spread from animal to human, and
visa-versa, monkey handlers who work with Ebola
ridden monkeys have broken out with the infamous
hemorragic fever. The animal-to-human spread of
the virus has also killed off African tribes
that eat animals with high titers of the deadly
virus.
Ebola is an infectious disease of many faces.
It has strains, such as Mayinga, or Cardinal,
which are mainly named after people, or places
that they are discovered in. Strains are
slightly different versions of a certain virus.
Ebola.s three types that are known are: Ebola
Zaire, Ebola Sudan, and Ebola Reston. Ebola
Zaire was first discovered in 1976 in Zaire. It
is the deadliest disease of all of the Ebola
strains with a 9 out of 10 kill rate (see fig.
1-1). Ebola Sudan kills over 1/2 of the people
it comes in contact with. It was discovered in
1976 also. Ebola Reston was named after Reston,
Virginia, which had a shipment of cynomolgus
macaques, a type of monkey, infect a whole
monkey house with Ebola. Ebola Reston has
never killed anyone, but it killed 80% of the
monkeys that it devastated.
Ebola also has a very close cousin, Marburg.
Under an electron microscope, they are clearly
filoviradae. Filoviruses are characterized by
their notorious for their nucleotide with
strands, or .tails., which make it look like a
.cheerio with a tail.. Marburg, which
obliterates one in four of its victims, was
named after a city in Germany. Marburg, Germany
received a shipment of Marburg monkeys from
Uganda that infected 31 people, killing 7 of
them. In later years five more people broke out
with the dire Marburg virus, destroying all but
one of them. Marburg and Ebola both have to be
identified under an electron microscope.
Marburg was discovered before Ebola (see fig.
1-2), so when Ebola Zaire swept through Africa
in 1976, it was mistaken as milder version,
Marburg.
Ebola has been traced to Africa, where the
majority of cases occur, and the Philippines, in
which monkeys had been found with Ebola Reston.
Most of our knowledge of Ebola came in 1976,
when the biggest outbreak occurred. It stormed
through Zaire wiping out complete villages. In
all 550 cases were reported with 430 fatalities
When USAMRIID led an investigation to find
where Ebola was found in nature, they traced it
to Kitum Cave, in Zaire. As Colonel Gene
Johnson said, .I.m completely sure we have
finally found the true hiding place of Ebola..
After extensive testing of nearly 10,000 animals
and insects, they found no trace of Ebola.
Other expeditions followed, with the same
disappointments as the Kitum Cave search.
Ebola and other filoviruses kill people by
decomposing the body before it does away with
its victims. Usually their organs liquefy
before they .crash. in a gruesome instance in
which blood and liquefied tissue spew from every
orifice in the body. The virus is composed of a
nucleus, and strands of RNA, for replication.
It makes its living by taking over cells and
bursting them creating an amplified amount of
virus. In some deaths, the virus disfigures the
corpse so badly that it is not recognizably
human. Once you get Ebola chances of survival
are minimal.
With all that Ebola can do, we still haven.t
found a certain cure. Radiation therapy had
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