Alzheimers Disease Essay, Research Paper
ALZHEIMER.S DISEASE
Alois Alzheimer was the first man to discover Alzheimer.s disease. Before this discovery,
the illness was classified as insanity. There is now a more sensitive understanding of this
disease. Alzheimer.s is a disease that slowly, but surely, causes one to lose his memory.
Symptoms are simple like one not being able to remember where he placed his keys.
Slowly he begins to forget names and telephone numbers until eventually most of his
memory is gone.
Forsyth and Ritzline claim that Alzheimer.s affects mainly middle-aged and older
people, although there has been one case of a twenty-eight year old having this disease.
Alzheimer.s affects women more than men. Forsyth and Ritzline state that this disease has
affected over 4 million people in the U.S. and the number is rising. By the middle of the
twenty first century over 14 million Americans are expected to have Alzheimer.s disease.
Ten percent of the individuals who are 65 years and older have this disease or the early
onsets. For individuals 85 and older, the ten percent rises to an astounding 42.7 percent.
One can see that the chance of getting this disease increases with age.
Cohen and Eisdorfer say many scientists have attempted to find medications that
may cure or prevent this terrible disease; however, they have not had much luck. Some
medications available to Alzheimer.s victims only treat disorders like sleeping,
nervousness, and anxiety. These are called antipsychotic medications like Thorazine,
Prolaxin, and Haldol.
Cohen and Eisdorfer say that in addition to antipsychotic medications there are
two other major categories of medications: anti-inflamitory and psychotropic.
Anti-inflamitory drugs are used to reduce inflammation and can keep the healthy tissue of
the brain from dying. Psychotropic dugs affect mental activity and are also used to treat
behavior. .Psychotropic. is a word that pertains only to the drugs that help influence the
behavior of patients, their brain, and their emotions. Sleepiness, costipation, blurred
vision, dry mouth, and bladder problems are all common side effects of people taking
psychotropic drugs.
Mike Akins states cognex and aricept are both psychotropic drugs. Cognex was
the first drug approved by the Federal Drug Administration (FDA) to help fight against
Alzheimer.s. Cognex is taken four times a day, and its side effects are horrible compared
to aricept. Aricept is a new drug recetly approbed by the FDA to help fight against
Alzheimer.s Aricept may more commonly be called by its generic name donepezil. Aricept
is only taken at bedtime. Its side affects make some people feel dizzy or light-headed.
This drug also can possibly be a big threat to patients who have certain heart conditions.
Aricept threatens people because it can lower their heart rate. Aricept does have some
advantages over cognex. Cognex requires liver function monitoring. This means that
blood tests have to be taken quite often. Aricept does not have to be monitored, and the
side effects seem to be more tolerable than those of cognex. Both aricept and cognex
make patients function intellectually about the same.
Fackelmann claims that all these drugs have helped in the fight against
Alzheimer.s, but recently scientists have discovered that estrogen also helps. .Estrogen
has been shown to influence several areas in the brain that are involved in cognition and
behavior,. says researcher Uriel Halbreich of the State University of New York at Buffalo.
Estrogen may be the miracle drug we have been searching for in the treatment of
Alzheimer.s disease.
Wilkinson says that Alzheimer.s is thought of as occurring in three stages.
However, these three stages have no decisive point where one stage ends and another one
starts. In the first stage, the patient is absent-minded, tired, and unresponsive. Memory
loss is crucial because when it is lost, it is gone forever. The patient does not want to
change clothing, return phone calls, or keep appointments. The patient also does not care
anything about learning new information. In the second stage, the patient may not be able
to recognize family members, places, people, or events. He or she may not remember
anything about the previous day. The patient may also begin to wander about at night
while the rest of the family is sleeping. Eventually the third stage starts; by this time, the
losses are very obvious. The patient.s walking becomes difficult; he or she may fall and
seriously injure himself. Short term and long term memory no longer exists, and words
and sentences are repeated. He or she babbles on and at times screams, grunts, or groans.
Estrogen is a body hormone all women have. Waters claims Howard Fillit was the first
person to connect the benefits of estrogen with Alzheimer.s disease. Estrogen
Replacement Therapy has been proved to fight
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